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Booster dose of six vaccines for strong immune response?

The new variant – Omicron has given a jolt to all globally since the world had just started to open up and economies showing a positive trend.

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New Variant
Source: @Business Standard

The new variant – Omicron has given a jolt to all globally since the world had just started to open up and economies showing a positive trend. But with 21 confirmed cases in India, there is a need to safeguard ourselves and understand that the pandemic is far from over.

The total number of confirmed COVID-19 cases due to the Omicron variant increased five times overnight as nine people in Rajasthan, seven in Pune and one in Delhi tested positive for the new strain on Sunday. The total count stood at 21. Delhi’s first patient infected with the Omicron variant is a 33-year-old male who returned from Tanzania recently. He is fully vaccinated and is at present undergoing treatment at the Capital’s Lok Nayak Hospital.

Among the nine cases confirmed in Jaipur, health officials are concerned about a surge in infections within a cluster of people associated with a four-member family from South Africa. The family had attended a wedding in Jaipur on November 28, 2021.

In the Pune Metropolitan Region, a woman of Indian origin from Nigeria and her two daughters and their three contacts tested positive for Omicron. Another man who had travelled to Pune from Finland via Mumbai also tested positive for the variant.

Amid questions about whether the Omicron variant may cause milder illness compared to the previous strains, evidence from initial cases is limited. However, among 70 cases reported in Europe that provided information on disease severity, half of the patients were asymptomatic and half had mild symptoms, reported the European Centre for Disease Prevention and Control.

No cases of severe disease were reported and there were no hospitalisations or deaths. The European agency, however, said that data on hundreds of cases will be needed to accurately assess the complications, and it could take weeks. Most cases reported in Europe have been in younger people thus far, who were fully vaccinated, and therefore, less likely to develop severe disease.

This means that there is an urgent need for everyone to get vaccinated. A total of 127.93 crore doses have been administered across the country till Sunday, with over 85% of the 18-plus population covered with at least one dose. This is a positive move.

But there was a case on December 3, 2021, where an Italian man tried to avoid the vaccine. He wore a fake arm. Remember that vaccination is for our good. There have been enough studies that show there are mild symptoms for those who are double jabbed.

Results of the COV-BOOST multicenter phase II trial show that the booster dose of six vaccines generated a strong immune response in persons who had completed their primary vaccination with either the Oxford-AstraZeneca vaccine or the Pfizer-BioNTech vaccine. The vaccines studied included Oxford-AstraZeneca, Pfizer-BioNTech, Novavax, Janssen, Moderna, Valneva and Curevac. The side effects of all vaccines were minor.

For the trial, 2878 participants were enrolled in the month of June; they had received two doses of either Pfizer or Oxford-AstraZeneca (first dose in December 2020, January 2021 or February 2021). The study was conducted at 18 sites in the UK.

“Participants had received their first doses of Oxford-AstraZeneca or the Pfizer-BioNTech vaccines in December 2020, or January, or February, and second doses at least 70 days (for Oxford–AstraZeneca) or 84 days (for Pfizer-BioNTech)” before study entry. Anti-spike protein IgG generated was evaluated at 28 days.

In persons who had taken the Oxford vaccine as their primary vaccination, the mean anti-spike protein antibody (IgG) after 28 days ranged from 1.8 times in the half Valneva group to 32.3 higher in the m1273 group. After two doses of the Pfizer-BioNTech vaccine, the booster dose increased the spike IgG (mean) from 1.3 times in the half Valneva group to 11.5 times in the m1273 group.

“GMRs for wild-type cellular responses compared with controls ranged from 1.0 for half VLA to 4.7 for m1273 vaccine”. The response to booster doses was comparable between the participants aged 30–69 years and those aged 70 years and older. The most common reported side effects after booster dose were injection site pain, muscle soreness and fatigue.

This trial has demonstrated the effectiveness of all vaccines tested in boosting immunity following initial immunization with Oxford-Astra and Pfizer vaccines. All the booster vaccines studied were found to increase the immune response 28 days after initial vaccination with both Oxford-AstraZeneca vaccine doses. After the two Pfizer vaccine doses, all vaccines except Valneva boosted the immune response. All vaccines were found safe to be used.

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Lifestyle

The ultimate kit for the body

Keeping fit during the present pandemic and increase immunity to fight the looming third wave is the best way to move forward.

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two girls doing pussups
Photo by bruce mars on Unsplash

We all want that perfect body. More so today due to the COVID-19 ad need to build our immunity to prevent getting infected. While there are many things that one can do, we are somewhat restricted since not everything is open – gyms with 50 per cent occupancy and swimming pools not open yet.

But this doesn’t mean that we have to totally give up on the exercise. In fact, this is perhaps the best time to put on your shoes and get that perfectly healthy body that one always wanted. Here is a list of super-easy hacks that can actually help without much hassle.

Lightweight shoes

If one is chasing something then running is a must. More so, if one wants to lose weight or clear the cobwebs — mental and physical problems. Running will help burn those extra calories that one may have put or are eating because one is at home. Early mornings are usually the most soothing time to hit the road. There are fewer people. This means that there is social distancing. A good pair of shoes can achieve mental peace and that body goal.

Hydration factor

Drinking enough water is not many people’s priority despite being aware of its multiple benefits, right from good skin to weight loss it curbs all problems. What can be better than plain water?

Doctors and nutritionists agree that drinking eight to 10 glasses of water has proven to help in weight loss much faster. Many celebs mention detox water in their diet. The digestive system is dependent on your water drinking habits. Promise the body to stay hydrated properly. Take four cups of water, add one sliced cucumber and sliced lemon. Refrigerator before drinking throughout the day.

Fitness tracker

Since the time this gadget has come in, it has changed the lives of many. However, there are people out there who don’t monitor their workouts. It is very important to have a workout journal, it helps you track down physical activity, check body composition, and have a monthly target for effective and faster weight loss.

Since many of us are still working from home, tracking workout patterns can be difficult for many. This is when technological innovations like fitness trackers can be of great help as it helps us to track heart rate 24/7, steps, distance, calories burned, hourly activity, active minutes, floors climbed.

All the busy people out there trying to strike a balance between work and gym can simply add this to keep a count on their day-to-day physical activity.

Dumbbells

Weight always adds extra power to the weight loss journey and that is why people usually tend to join the gym. But with only 50 per cent occupancy allowed, it may not be possible to lift weights every day.

Invest in good dumbbells. They are great when it comes to curbing extra fats from the body. Buying dumbbells prevents one to spend extra on a gym subscription every month. Also, it can be an added benefit as one can do it whenever there is time — early morning or late night.

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Lifestyle

What to do when you miss your ex

It is always tough to deal with a situation when you have to get over the ex. Here are 16 ways to move on when you still love your ex.

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What to do when you miss your ex

It is always tough to deal with a situation when you have to get over the ex. You miss the closeness you shared and the love you still have for that person unfortunately the other person has moved on and so should you. Here are 16 ways to move on when you still love your ex.

What to do when you miss your ex

1. If you love a person, fight for him/her as hard as you can. No matter how strange or weird it seems, fight for the love of your life. You may not succeed but at least you tried. This will help you avoid regrets in the future that you may have with regard to that relationship.

2. If despite fighting for that relationship, the person leaves, the next step is how to let go. You must accept the reality. You need to tell your brain it is all over.

3. There’s an adage: If you love someone set him/her free, if it’s meant to be, they will come back to you. Leave everything to destiny.

4. Stop thinking about that person all the time or the good times you spent with each other. This will hurt you. Return his/her things.

5. Focus on other important things in life. Focus on your job, family, and friends.

6. Stay away from all social media accounts for some time. You may be tempted to look at what he/she is doing. This is a strict no-no.

7. It is just as important to stay away from common family and friends. Communicating with them will only remind you of him/her. If you don’t do this, it will only make it hard for you to forget him/her.

8. Always have a friend whom you can speak with regarding your ex. You need a person who can listen to you instead of pass judgment on your relationship. Look for a person whom you trust and who understands what you are going through.

9. It is important to give yourself time to get over the ex. Be patient. Don’t force yourself to heal fast. Some people take more time to get over it than others.

10. Depression is a common symptom when the ex walks out. Don’t brood. Surround yourself with people who care about you. Ask a friend to give you company. Or go stay with a friend. Take yourself out of the situation that was familiar.

11. If you don’t a family member close by, take up a hobby or an activity that will keep your mind from thinking about the ex. Take up painting or learn a new skill. A new skill can help you further your career and advance professionally. It will give you a sense of achievement.

12. Your ex is not the only person you love. There are many others who can appreciate the love you shower on them.

13. Learn to love yourself. Tell yourself that you can love yourself. You can be your best friend. Sleep properly, treat yourself well, avoid stress and eat well.

14. Don’t dwell on the pain. It will make you eat junk food and engage in unhealthy activities. Instead of developing destructive habits and up in a worse situation look for constructive things to do.

15. Find romance elsewhere. You may think that your ex was the love of your life and you won’t find anyone else. This is not true. You gave to move ahead — despite the temporary heartbreak. Love should not be restricted to any person. You can keep a pet and show it, love.

15. It is not very easy to be happy for your ex since you are miserable but it’s a sign of maturity. Love should not be selfish. It should be about being happy for others even if it is your ex. Like you celebrate your friend’s success, do the same with your ex.

16. Be happy in all situations. Life is about ups and downs. It is not all roses. It is important to be happy. It may not be possible for you to imagine that it is possible to be happy without the love of your life but this is very much doable. Remember, after a dark night, there’s bright sunshine the next day.

Disclaimer: The above list is not exhaustive. The idea of this article is to let people know that it is possible to move ahead in life. Always take professional help as and when the need arises.

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Lifestyle

Best five ways you can charge your electric vehicle

Since the time electric vehicles have come into India, the question is how to easily charge them. Here are a few tips. Read on…

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can you charge two electric cars at home
Source: @Inventya Ltd.

Electric vehicles are slowly but surely taking over the automotive market. With electric scooters joining the four-wheelers, the question is how to charge them efficiently. With their many benefits, ranging from reduced emissions to low running costs, it’s easy to see why they are becoming increasingly popular.

And while this uptick in demand is great news for the environment and our wallets, it does present one small challenge – how do we keep all those electric cars juiced up? Here are five easy ways suggested to charge your electric vehicles.

Plug into a standard household outlet

Most electric vehicles come up with a charging cord that plugs into a standard household outlet. This is the slowest way to charge your vehicle, but it’s also the most convenient one of all other options that already exist in the market because you can use normal outlets in your house. This is also known as ‘Trickle charging’.

Level 2 chargers can be used for both home and commercial charging stations

They use a 240 V (residential) or 208 V (commercial) plug and must be installed by a professional electrician. They can also be installed as part of a solar panel system. Level 2 chargers deliver 10 to 60 miles of range per hour of charging, which means they can fully charge an electric car battery in as little as two hours. They are an ideal option for both homeowners and business owners.

Charge your electric vehicle using public charging spots

This is the fastest way to charge up your EV vehicles. Several ultra-fast charging stations can provide more than 150kw of power. DC charging is 10X faster than trickle charge and can boost up your charging from 20%-80% within 40 minutes. The power does not flow continuously in this, as of the charging power gradually decreases as the battery percentage increases.

Battery swapping is an alternative

This is a good way to charge electric vehicles, which involves exchanging discharged batteries for charged ones. This de-links charging and battery usage, so the vehicle can stay in the operational mode with minimal downtime.

Induction pads

These are the breakthrough technology that will eliminate the need for charging cables but still let you charge up your car on the street outside your home? So-called induction charging pads work like the wifi charging pads for smartphones – magically charging up the unit without plugging it in.

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